Set in the tumultuous period of the Hussite Wars in 15th-century Central Europe, the story follows Reinmar of Bielawa, a young medical student and herbalist, who becomes embroiled in a series of dangerous adventures after a romantic entanglement goes awry. As he flees from the vengeful family of his lover, Reinmar encounters a diverse cast of characters, including knights, mercenaries, and mystical beings, all while navigating the complex political and religious tensions of the era. The narrative weaves together historical events with elements of fantasy, exploring themes of love, betrayal, and the quest for knowledge amidst chaos.